CAS:
CAS：159351-69-6
货号：E6717
储存条件：粉末-20°C可保存3年；液体-80°C可保存12月。
产品描述
Everolimus is an inhibitor of mTOR through binding FKBP12 with IC50 of 1.6-2.4 nM, which also shows inhibition in several hormone therapy–sensitive ERb breast cancer xenograft models like MCF7 and HCC1500, as well as three patient-derived primary explant models BR0555, CTC174, and HBCx3. Up to now, AZD2014 enters Phase 1 trial in solid tumours.
储存液制备 | 质量 | 1 mg | 5 mg | 10 mg |
1 mM | 1.0436 mL | 5.2180 mL | 10.4359 mL | |
5 mM | 0.2087 mL | 1.0436 mL | 2.0872 mL | |
10 mM | 0.1044 mL | 0.5218 mL | 1.0436 mL |
产品信息
别名 | RAD001;SDZ RAD | |
CAS号 | 159351-69-6 | |
分子式 | C53H83NO14 | |
分子量 | 958.22 | |
溶解度
| DMSO | 360.0 mg/mL (375.7 mM) warming |
Water | lnsoluble | |
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