货号：U0492
储存条件：粉末-20°C可保存3年；液体-80°C可保存12月。
产品描述
Urolithin A, the intestinal microbial metabolite of ellagic acid, has the characteristics of anti-inflammatory, anti-proliferation and anti-oxidation. Urolithin A imparted cognitive protection by protecting neurons from death and triggering neurogenesis via anti-inflammatory signaling in APP/PS1 mice. Urolithin A shows antiproliferative effects and inhibits T24 and Caco-2 cell growth with IC50s of 43.9 and 49 μM, respectively. Moreover, inhibiting effects on cell proliferation in a dose-dependent manner (IC50 = 137 ± 8.2 μM) after 24 h treatment of Urolithin A. Administration of 100–250 μM of Urolithin A results in the down-regulation of β-catenin/TCF dependent transcriptional activation in HepG2 cells.
产品信息
CAS号 | 1143-70-0 | |
分子式 | C13H8O4 | |
分子量 | 228.20 | |
溶解度 | DMSO | 44.0 mg/mL (192.8 mM) |
Water | lnsoluble | |
Ethanol | lnsoluble | |
说明书下载
