货号：Z8102
储存条件：粉末-20°C可保存3年；液体-80°C可保存12月。
产品描述
Z-DEVD-FMK (1–200 μM) inhibits D4-GDI cleavage and apoptosis in a concentration-dependent manner. Z-DEVD-FMK reduces ceramide-induced cardiomyocyte death and significantly inhibits the activation of caspase 3. Z-DEVD-FMK (100μM) attenuates OxyHb-induced cell detachment, reduced caspase-2 and -3 activities, abolishes OxyHb-induced DNA ladders, and prevents OxyHb-induced cleavage of PARP in cultured brain microvessel endothelial cells. Z-DEVD-FMK (100 μM) blocks MPP+-induced increases in caspase-3 enzyme activity. Z-DEVD-FMK dose dependently blocks 6-OHDA-induced apoptotic cell death with IC50 of 18 μM.
储存液制备 | 质量 | 1 mg | 5 mg | 10 mg |
1 mM | 1.4955 mL | 7.4776 mL | 14.9552 mL | |
5 mM | 0.2991 mL | 1.4955 mL | 2.9910 mL | |
10 mM | 0.1496 mL | 0.7478 mL | 1.4955 mL |
产品性质
CAS号 | 210344-95-9 | |
分子式 | C30H41FN4O12 | |
分子量 | 668.66 | |
溶解度 | DMSO | 99.0 mg/mL (148.1 mM) |
Water | lnsoluble | |
Ethanol | lnsoluble | |
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