货号：L7411
储存条件：粉末-20°C可保存3年，液体-80°C可保存12月。
产品描述
Leupeptin is a reversible and competitive serine/cysteine protease inhibitor which can inhibit proteolysis plasmin, trypsin and papain but not chymotrypsin. Oral administration of leupeptins exhibited an anti-inflammatory effect on edema. It inhibited thrombokinase reaction and coagulation of blood of human and rabbit, but not in rats and dogs. Leupeptin is also used as a cathepsin B inhibitor. Leupeptin inhibited calpain activity with IC50 of 0.14 μM.
作用机制
Leupeptin is competitive with substrates. The free aldehyde group plays a role in the activities
储存液制备 | 质量 | 1 mg | 5 mg | 10 mg |
1 mM | 1.0513 mL | 5.2566 mL | 10.5131 mL | |
5 mM | 0.2103 mL | 1.0513 mL | 2.1026 mL | |
10 mM | 0.1051 mL | 0.5257 mL | 1.0513 mL |
产品性质
CAS号 | 103476-89-7 | |
分子式 | C40H78N12O12S | |
分子量 | 951.19 | |
溶解度 | DMSO | 80.0 mg/mL (84.1 mM) |
Water | 78.0 mg/mL(82.0 mM) | |
Ethanol | 78.0 mg/mL(82.0 mM) | |
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